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Mangosteen Pericarp Extract

The pericarp of Garcinia mangostana or mangosteen was removed air-dried ground to fine powder and macerated with ethanol. In the present study the inhibitory effect of hot water extracts of mangosteen Garcinia mangostana L pericarp WEM on the formation of pentosidine one of AGEs in vitro and in vivo and the remedial effect on skin conditions were measured.


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The highest dose 800 mgkg was most effective in terms of anti-oxidative and anti-inflammatory activities.

Mangosteen pericarp extract. 1Ethanol which is an amphipathic solvent could be a potential solvent to extract the α-mangostin compound and other xanthones derivatives from mangosteen pericarp Yoshimura et. 31Mangosteen pericarp extract MPE induced a remarkable decrease in BMI from 086 to 081 gmcm 2 while curcuma either alone or in combination was. 13Mangosteen pericarp extract significantly inhibited the formation of VEGF receptor 1 and reduced NF-κB iNOS H 2 O 2 and H1F1-α expression.

Including mangosteen pericarp and alcoholic extracts of mangosteen pericarp are used as health foods 25 26. Products containing mangosteen juice or extract are a fast growing segment of the functional beverages market. 1Mangosteen is used for obesity and a serious gum infection periodontitis.

A neutraceutical beverage comprising pericarp extract from the Garcinia mangostana L. Mangosteen plant and juice from mangosteen fruit pulp preferably combined with juice from at least one of four other ingredients selected from red grapes lycium sea buckthorn and apple preferably obtained from powdered extract of mangosteen pericarp and a mixture of fruit concentrate andor powdered. Mangosteen has its primary nutrient content found not in its sweet inner white fruit but rather in its bitter outer hull the pericarp.

This ratio was selected based on polarity of extract and its compound. Mangosteen from Emerald Labs is made purely from the active pericarp portion. 30mangosteen Pericarp extract against cariogenic Streptococcus mutans 16.

In Japan therefore mangosteen pericarp extract has been more widely used as a raw material for. The extract obtained was then filtered and extracted with water for 48 h. 23 December 2019 bio-based solvent mangosteen pericarp phenolic compound antioxidant.

The strong anti bacterial activity of the extract suggests that it is a good drug of choice for. In the present study the inhibitory effect of hot water extracts of mangosteen Garcinia mangostana L pericarp WEM on the formation of pentosidine one of AGEs in vitro and in vivo and the remedial effect on skin conditions were measured. CONCLUSION The extract from mangosteen pericarp was effective against Staphylococcus aureus Staphylococcus albus Micrococcus lutus.

Keywords Article history Received. 144578 for methanol 100598 for ethanol and 142898 for ethyl acetate while compared to the. 18 June 2019 Received in revised form.

It is also used for muscle strength diarrhea and skin conditions but there is no good scientific evidence to support. In particular it has been reported that a water soluble component of mangosteen pericarp has a strong anti-oxidative effect 27. WEM significantly inhibited pentosidine formation during gelatin incubation with ribose.

It was following the principle of adsorption and partition that would give spot on the TLC result as shown in Table 2. Thus bio-based solvents particularly PG were suitable for the recovery of active phenolic compounds form MP. Comparison of alpha-mangostin level in the mangosteen pericarp extract for each eluent ie.

1Plant material and preparation of the extract. 1the extract was enhanced when VCO was used. 6 December 2019 Accepted.

Fresh and healthy mangosteen leaves were collected washed thoroughly with distilled water incised into small pieces and air-dried. Mangosteen is commonly used to. WEM significantly inhibited pentosidine formation during gelatin incubation with ribose.

The aqueous fraction thus obtained was then concentrated with a rotary evaporator at 40C and dried with a freeze dryer. TLC results of mangosteen pericarp extract Spot Rf Color Visual UV λ254 UV λ366 1 0875 - Purple - 2 0513 - Purple -. 13The pericarp of mangosteen fruit has been used in traditional medicine in Southeast Asia for centuries to treat infection wounds inflammation and diarrhea.

About 25 g of thus finely cut mangosteen leaves were weighed and transferred into 500-ml beaker containing 100 ml distilled water mixed well and boiled for 25 min.


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